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Cardiac Imaging References

2020

Total: 40

Cassady E. Rupert, Tae Yun Kim, Bum-Rak Choi, and Kareen L. K. Coulombe 

Human Cardiac Fibroblast Number and Activation State Modulate Electromechanical Function of hiPSC-Cardiomyocytes in Engineered Myocardium.

Stem Cells Int. 2020; 2020: 9363809.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye 


Jessica M. Miller, Moustafa H. Meki, Qinghui Oua, Sharon A. George, Anna Gams, Riham R.E. Abouleisa, Xian-Liang Tang, Brooke M. Ahern, Guruprasad A. Giridharan, Ayman El-Baz, Bradford G. Hill, Jonathan Satin, Daniel J.Conklin, Javid Moslehi, Roberto Bolli, Alexandre J.S. Ribeiro, Igor R. Efimov, Tamer M.A. Mohamed 

Heart slice culture system reliably demonstrates clinical drug-related cardiotoxicity.

Toxicology and Applied Pharmacology, Volume 406, 2020,115213
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye 


B. N. Napiwocki, D. Lang, A. Stempien, J. Zhang, R. Vaidyanathan, J. C. Makielski, L. L. Eckhardt, A. V. Glukhov, T. J. Kamp, W. C. Crone 

Aligned human cardiac syncytium for in vitro analysis of electrical, structural, and mechanical readouts.

Biotechnology and Bioengineering. 2021; 118: 442– 452.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye 


Zeinab Neshati, Martin J Schalij, Antoine A F de Vries 

The proarrhythmic features of pathological cardiac hypertrophy in neonatal rat ventricular cardiomyocyte cultures

J Appl Physiol (1985). 2020 Mar 1;128(3):545-553.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye 


Louise Reilly, Francisco J Alvarado, Di Lang, Sara Abozeid, Hannah Van Ert, Cordell Spellman, Jarrett Warden, Jonathan C Makielski, Alexey V Glukhov, Lee L Eckhardt 

Genetic Loss of IK1 Causes Adrenergic-Induced Phase 3 Early Afterdepolariz ations and Polymorphic and Bidirectional Ventricular Tachycardia

Circ Arrhythm Electrophysiol. 2020 Sep;13(9):e008638.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Weiwei Jiang, Xingjian Hu, Fei Li, Geng Li, Yin Wang  

Adrenoceptor Responses in Human Embryonic Stem Cell-Derived Cardiomyocytes: a Special Focus on Electrophysiological Property.

J Pharmacol Exp Ther. 2020 Jun;373(3):429-437.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye 


Aida Oliván-Viguera, María Pérez-Zabalza, Laura García-Mendívil, Konstantinos A. Mountris, Sofía Orós-Rodrigo, Estel Ramos-Marquès, José María Vallejo-Gil, Pedro Carlos Fresneda-Roldán, Javier Fañanás-Mastral, Manuel Vázquez-Sancho, Marta Matamala-Adell, Fernando Sorribas-Berjón, Javier André Bellido-Morales, Francisco Javier Mancebón-Sierra, Alexánder Sebastián Vaca-Núñez, Carlos Ballester-Cuenca, Miguel Ángel Marigil, Cristina Pastor, Laura Ordovás, Ralf Köhler, Emiliano Diez & Esther Pueyo  

Minimally invasive system to reliably characterize ventricular electrophysiology from living donors.

Scientific Reports volume 10, Article number: 19941 (2020).
MiCAM05 ULTIMA Isolated Heart Voltage Sensitive Dye 


Yan Liu, Xueqi Xu, Yuhao Zhang, Mingzhu Li, Jiamengyi Guo, Caichuan Yan, Fang Wang, Yuexin Li, Yunqi Ding, Baoxin Li, and Pan Fan  

Thioridazine Induces Cardiotoxicity via Reactive Oxygen Species-Mediated hERG Channel Deficiency and L-Type Calcium Channel Activation.

Oxidative Medicine and Cellular Longevity, vol. 2020, Article ID 3690123, 17 pages, 2020.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Yin‐Yu Lam, Wendy Keung, Chun‐Ho Chan, Lin Geng, Nicodemus Wong, David Brenière‐Letuffe, Ronald A. Li and Yiu‐Fai Cheung  

Single‐Cell Transcriptomics of Engineered Cardiac Tissues From Patient‐Specific Induced Pluripotent Stem Cell–Derived Cardiomyocytes Reveals Abnormal Developmental Trajectory and Intrinsic Contractile Defects in Hypoplastic Right Heart Syndrome.

J Am Heart Assoc. 2020 Oct 20; 9(20): e016528.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye 


Akio Shimizu, Dimitar P Zankov, Akira Sato, Masahiro Komeno, Futoshi Toyoda, Satoru Yamazaki, Toshinori Makita, Taichi Noda, Masahito Ikawa, Yoshihiro Asano, Yohei Miyashita, Seiji Takashima, Hiroshi Morita, Taisuke Ishikawa, Naomasa Makita, Masahito Hitosugi, Hiroshi Matsuura, Seiko Ohno, Minoru Horie, Hisakazu Ogita  

Identification of transmembrane protein 168 mutation in familial Brugada syndrome.

FASEB J. 2020 May;34(5):6399-6417.
MiCAM03-N256 Isolated Heart Voltage Sensitive Dye 


Peter Hanna, Michael J. Dacey, Jaclyn Brennan, Alison Moss, Shaina Robbins, Sirisha Achanta, Natalia P. Biscola, Mohammed A. Swid, Pradeep S. Rajendran, Shumpei Mori, Joseph E. Hadaya, Elizabeth H. Smith, Stanley G. Peirce, Jin Chen, Leif A. Havton, Zixi (Jack) Cheng, Rajanikanth Vadigepalli, James Schwaber, Robert L. Lux, Igor Efimov, John D. Tompkins, Donald B. Hoover, Jeffrey L. Ardell, Kalyanam Shivkumar  

Innervation and Neuronal Control of the Mammalian Sinoatrial Node: A Comprehensive Atlas.

bioRxiv 2020.10.28.359109.
MiCAM05 ULTIMA Isolated Heart Voltage Sensitive Dye 


Jeffrey Abrams, Daniel Roybal, Nourdine Chakouri, Alexander N. Katchman, Richard Weinberg, Lin Yang, Bi-xing Chen, Sergey I. Zakharov, Jessica A. Hennessey, Uma Mahesh R. Avula, Johanna Diaz, Chaojian Wang, Elaine Y. Wan, Geoffrey S. Pitt, Manu Ben-Johny, and Steven O. Marx  

Fibroblast growth factor homologous factors tune arrhythmogenic late NaV1.5 current in calmodulin binding–deficient channels.

JCI Insight. 2020 Oct 2; 5(19): e141736.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Stefanie Fenske, Konstantin Hennis, René D. Rötzer, Verena F. Brox, Elvir Becirovic, Andreas Scharr, Christian Gruner, Tilman Ziegler, Verena Mehlfeld, Jaclyn Brennan, Igor R. Efimov, Audrys G. Pauža, Markus Moser, Carsten T. Wotjak, Christian Kupatt, Rasmus Gönner, Rai Zhang, Henggui Zhang, Xiangang Zong, Martin Biel and Christian Wahl-Schott  

cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells.

Nat Commun. 2020; 11: 5555.
MiCAM05 ULTIMA Isolated Heart Voltage Sensitive Dye 


Tim R. Eijgenraam, Bastiaan J. Boukens, Cornelis J. Boogerd, E. Marloes Schouten, Cees W. A. van de Kolk, Nienke M. Stege, Wouter P. te Rijdt, Edgar T. Hoorntje, Paul A. van der Zwaag, Eva van Rooij, J. Peter van Tintelen, Maarten P. van den Berg, Peter van der Meer, Jolanda van der Velden, Herman H. W. Silljé & Rudolf A. de Boer   

The phospholamban p.(Arg14del) pathogenic variant leads to cardiomyopathy with heart failure and is unresponsive to standard heart failure therapy.

Scientific Reports volume 10, Article number: 9819 (2020)
MiCAM05 ULTIMA Isolated Heart Voltage Sensitive Dye 


Ting-Tse Lin, Yen-Ling Sung, Jhen-Yang Syu, Kia-Yuan Lin, Hung-Jui Hsu, Min-Tsun Liao, Yen-Bin Liu, Shien-Fong Lin  

Anti-Inflammatory and Antiarrhythmic Effects of Beta Blocker in a Rat Model of Rheumatoid Arthritis.

J Am Heart Assoc. 2020 Sep 15;9(18):e016084.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Beibei Du, Praloy Chakraborty, Mohammed Ali Azam, Stéphane Massé, Patrick F.H. Lai, Ahmed Niri BEng, Daoyuan Si, Paaladinesh Thavendiranathan, Husam Abdel-Qadir, Filio Billia, Kumaraswamy Nanthakumar  

Acute Effects of Ibrutinib on Ventricular Arrhythmia in Spontaneously Hypertensive Rats.

JACC: CardioOncology Volume 2, Issue 4, November 2020, Pages 614-629
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Yen‐Ling Sung, Ting‐Tse Lin, Jhen‐Yang Syu, Hung‐Jui Hsu, Kai‐Yuan Lin, Yen‐Bin Liu, Shien‐Fong Lin  

Reverse electromechanical modelling of diastolic dysfunction in spontaneous hypertensive rat after sacubitril/valsartan therapy.

ESC Heart Failure 2020; 7: 4040–4050
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Jiyoung Lee, Akito Sutani, Rin Kaneko, Jun Takeuchi, Tetsuo Sasano, Takashi Kohda, Kensuke Ihara, Kentaro Takahashi, Masahiro Yamazoe, Tomohiro Morio , Tetsushi Furukawa, Fumitoshi Ishino  

In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix.

Nat Commun. 2020 Sep 3;11(1):4283.
MiCAM ULTIMA Voltage Sensitive Dye 


Gerard A. Marchal, Arie O. Verkerk, Rajiv A. Mohan, Rianne Wolswinkel, Bastiaan J. D. Boukens, and Carol Ann Remme  

The sodium channel NaV1.5 impacts on early murine embryonic cardiac development, structure and function in a non‐electrogenic manner.

Acta Physiol (Oxf). 2020 Oct; 230(2): e13493.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Po-Cheng Chang, Hung-Ta Wo, Hui-Ling Lee, Shien-Fong Lin, Yen Chu, Ming-Shien Wen, Chung-Chuan Chou  

Sacubitril/Valsartan Therapy Ameliorates Ventricular Tachyarrhythmia Inducibility in a Rabbit Myocardial Infarction Model.

J Card Fail. 2020 Jun;26(6):527-537.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Chung-Chuan Chou, Hui-Ling Lee, Yu-Chang Huang, Hung-Ta Wo, Ming-Shien Wen, Yen Chu, Po-Cheng Chang  

Single Bolus Rosuvastatin Accelerates Calcium Uptake and Attenuates Conduction Inhomogeneity in Failing Rabbit Hearts With Regional Ischemia-Reperfusion Injury.

J Cardiovasc Pharmacol. 2020 Jan;75(1):64-74.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Matthias Baudot, Eleonora Torre, Isabelle Bidaud, Julien Louradour, Angelo G. Torrente, Lucile Fossier, Leïla Talssi, Joël Nargeot, Stéphanie Barrère-Lemaire, Pietro Mesirca, and Matteo E. Mangoni  

Concomitant genetic ablation of L-type Cav1.3 (α1D) and T-type Cav3.1 (α1G) Ca2+ channels disrupts heart automaticity.

Sci Rep. 2020; 10: 18906.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Chung-Chuan Chou, Hui-Ling Lee, Gwo-Jyh Chang, Hung-Ta Wo, Tzung-Hai Yen, Ming-Shien Wen, Yen Chu, Hao-Tien Liu, Po-Cheng Chang  

Mechanisms of ranolazine pretreatment in preventing ventricular tachyarrhythmias in diabetic db/db mice with acute regional ischemia-reperfusion injury.

Sci Rep. 2020 Nov 18;10(1):20032.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Sharon A George, Jaclyn A Brennan, Igor R Efimov  

Preclinical Cardiac Electrophysiology Assessment by Dual Voltage and Calcium Optical Mapping of Human Organotypic Cardiac Slices.

J Vis Exp. 2020 Jun 16;(160). doi: 10.3791/60781.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Angel Moreno, Richard D. Walton, and Jason D. Bayer  

Stretchable Conductive Fabric for Cardiac Electrophysiology Applications.

ACS Appl. Bio Mater. 2020, 3, 5, 3114–3122
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Young M Kim, Robert Lakin, Hao Zhang, Jack Liu, Ayaaz Sachedina, Maneesh Singh, Emily Wilson, Marco Perez, Subodh Verma, Thomas Quertermous, Jeffrey Olgin, Peter H Backx, Euan A Ashley  

Apelin increases atrial conduction velocity, refractoriness, and prevents inducibility of atrial fibrillation.

JCI Insight. 2020 Sep 3;5(17):e126525.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Ed White, Richard Walton, Sarbjot Kaur, Amelia Power, Michel Haïssaguerre, Olivier Bernus, Marie-Louise Ward  

Mechanical stimulation of endocardial Purkinje fibres can trigger ventricular arrhythmias.

bioRxiv 2020.08.10.234195
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Gregory S Hoeker, Carissa C James, Allison N Tegge, Robert G Gourdie, James W Smyth, Steven Poelzing  

Attenuating loss of cardiac conduction during no-flow ischemia through changes in perfusate sodium and calcium.

Am J Physiol Heart Circ Physiol. 2020 Aug 1;319(2):H396-H409.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Wenli Dai, Rangarajan D. Nadadur, Jaclyn A. Brennan, Heather L. Smith, Kaitlyn M. Shen, Margaret Gadek, Brigitte Laforest, Mingyi Wang, Joanna Gemel, Ye Li, Jing Zhang, Bruce D. Ziman, Jiajie Yan, Xun Ai, Eric C. Beyer, Edward G. Lakata, Narayanan Kasthuri, Igor R. Efimov, Michael T. Broman, Ivan P. Moskowitz, Le Shen, Christopher R. Weber  

ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.

Circulation Research. 2020;127:e28–e43
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Yu-An Chiou, Li-Kuan Cheng, Shien-Fong Lin  

Effects of high-frequency biphasic shocks on ventricular vulnerability and defibrillation outcomes through synchronized virtual electrode responses.

PLoS One. 2020; 15(5): e0232529.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Carolina Vasquez, Valeria Mezzano, Newman Kessler, Freja Swardh, Desiree Ernestad, Vanessa M. Mahoney, John Hanna & Gregory E. Morley  

Connexin43 expression in bone marrow derived cells contributes to the electrophysiological properties of cardiac scar tissue.

Scientific Reports volume 10, Article number: 2617 (2020)
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Louisa Mezache, Heather L. Struckman, Amara Greer-Short, Stephen Baine, Sándor Györke, Przemysław B. Radwański, Thomas J. Hund and Rengasayee Veeraraghavan  

Vascular endothelial growth factor promotes atrial arrhythmias by inducing acute intercalated disk remodeling.

Sci Rep. 2020; 10: 20463.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Srinivas Tapa, Lianguo Wang, Samantha D. Francis Stuart, Zhen Wang, Yanyan Jiang, Beth A. Habecker & Crystal M. Ripplinger  

Adrenergic supersensitivity and impaired neural control of cardiac electrophysiology following regional cardiac sympathetic nerve loss.

Scientific Reports volume 10, Article number: 18801 (2020)
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Zhen Wang, Srinivas Tapa, Samantha D Francis Stuart, Lianguo Wang, Julie Bossuyt, Brian P Delisle, Crystal M Ripplinger  

Aging Disrupts Normal Time-of-Day Variation in Cardiac Electrophysiology.

Circ Arrhythm Electrophysiol. 2020 Sep;13(9):e008093.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Alexander M Zolotarev, Brian J Hansen, Ekaterina A Ivanova, Katelynn M Helfrich, Ning Li, Paul M L Janssen, Peter J Mohler, Nahush A Mokadam, Bryan A Whitson, Maxim V Fedorov, John D Hummel, Dmitry V Dylov, Vadim V Fedorov  

Optical Mapping-Validated Machine Learning Improves Atrial Fibrillation Driver Detection by Multi-Electrode Mapping.

Circ Arrhythm Electrophysiol. 2020 Oct;13(10):e008249.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Duanyang Xie, Li Geng, Shuo Wang, Ke Xiong, Tingting Zhao, Guanghua Wang, Zhiqiang Feng, Fei Lv, Cheng Wang, Dandan Liang, Dan ShiMD, Xiue MaMD, Yi Liu, Jian Yang, Chao Zhang, Yi-Han Chen  

Cold-inducible RNA-binding protein modulates atrial fibrillation onset by targeting multiple ion channels.

Heart Rhythm Volume 17, Issue 6, June 2020, Pages 998-1008
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


V Olejnickova, D Sedmera  

What Is the Optimal Light Source for Optical Mapping Using Voltage- and Calcium-Sensitive Dyes?

Physiol Res. 2020 Aug 31;69(4):599-607
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Lianguo Wang, Antoinette Olivas, Samantha D Francis Stuart, Srinivas Tapa, Matthew R Blake, William R Woodward, Beth A Habecker, Crystal M Ripplinger  

Cardiac sympathetic nerve transdifferentiation reduces action potential heterogeneity after myocardial infarction.

Am J Physiol Heart Circ Physiol. 2020 Mar 1;318(3):H558-H565.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Andy On-Tik Wong, Nicodemus Wong, Lin Geng, Maggie Zi-ying Chow, Eugene K. Lee, Hongkai Wu, Michelle Khine, Chi-Wing Kong, Kevin D. Costa, Wendy Keung, Yiu-Fai Cheung, and Ronald A. Li  

Combinatorial Treatment of Human Cardiac Engineered Tissues With Biomimetic Cues Induces Functional Maturation as Revealed by Optical Mapping of Action Potentials and Calcium Transients.

Front Physiol. 2020; 11: 165.
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye 


Jaclyn A. Brennan, Qing Chen, Anna Gams, Jhansi Dyavanapalli, David Mendelowitz, Weiqun Peng, Igor R.Efimov  

Evidence of Superior and Inferior Sinoatrial Nodes in the Mammalian Heart.

JACC Clin Electrophysiol. 2020 Dec;6(14):1827-1840.
MiCAM ULTIMA MiCAM05 ULTIMA Isolated Heart Voltage Sensitive Dye 


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Cardiac Imaging