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Cardiac Imaging References

2021

Total: 27

Marion Pierre, Mohammed Djemai, Hugo Poulin, and Mohamed Chahine

NaV1.5 knockout in iPSCs: a novel approach to study NaV1.5 variants in a human cardiomyocyte environment.

Sci Rep. 2021; 11: 17168.
MiCAM03-N256 Cultured Cell Voltage Sensitive Dye Calcium Sensitive Dye


William Joyce, Koen T. Scholman, Bjarke Jensen, Tobias Wang, and Bastiaan J. Boukens

α1-adrenergic stimulation increases ventricular action potential duration in the intact mouse heart.

FACETS. 6(): 823-836.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Yayoi Honda, Jun Li, Aya Hino, Shinji Tsujimoto, and Jong-Kook Lee

High-Throughput Drug Screening System Based on Human Induced Pluripotent Stem Cell-Derived Atrial Myocytes ∼ A Novel Platform to Detect Cardiac Toxicity for Atrial Arrhythmias.

Front Pharmacol. 2021 Aug 3;12:680618.
MiCAM02-CMOS Cultured Cell Voltage Sensitive Dye 


Yung-Nan Tsai, Ya-Wen Hsiao, Shien-Fong Lin, Yi-Hsin Chan, Yu-Cheng Hsieh, Wei-Hua Tang, An-Sheng Lee, Yu-Ting Huang, Hsing-Yuan Li, Tze-Fan Chao, Satoshi Higa, Tsu-Juey Wu, Shih-Lin Chang, Shih-Ann Chen

Proinflammatory Cytokine Modulates Intracellular Calcium Handling and Enhances Ventricular Arrhythmia Susceptibility.

Front Cardiovasc Med. 2021 Mar 16;8:623510.
MiCAM02-CMOS Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Yali Zhao, Nicholas A James, Ashraf R Beshay, Eileen E Chang, Andrew Lin, Faiza Bashar, Abram Wassily, Binh Nguyen, Thao P Nguyen

Adult zebrafish ventricular electrical gradients as tissue mechanisms of ECG patterns under baseline vs. oxidative stress.

Cardiovasc Res. 2021 Jul 7;117(8):1891-1907.
MiCAM03-N256 Isolated Heart Voltage Sensitive Dye 


Fumin Fu, Michael Pietropaolo, Lei Cui, Shilpa Pandit, Weiyan Li, Oleg Tarnavski, Suraj S. Shetty, Jing Liu, Jennifer M. Lussier, Yutaka Murakami, Prabhjit K. Grewal, Galina Deyneko, Gordon M. Turner, Andrew K.P. Taggart, M. Gerard Waters, Shaun Coughlin, Yuichiro Adachi

Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models.

bioRxiv 2021.08.17.456655;
MiCAM03-N256 Isolated Heart Voltage Sensitive Dye 


Hyewon Park, Sangchul Lim, Seunghoon Lee, Dasom Mun, JiYoung Kang, Hyoeun Kim, Hyelim Park, Changsoo Kim, Sunho Park, Yeong Min Lim, Boyoung Joung

High Level of Real Urban Air Pollution Promotes Cardiac Arrhythmia in Healthy Mice.

Korean Circ J. 2021 Feb;51(2):157-170.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Kandace Thomas, Trevor Henley, Simone Rossi, M Joseph Costello, William Polacheck, Boyce E Griffith, Michael Bressan

Adherens junction engagement regulates functional patterning of the cardiac pacemaker cell lineage.

Dev Cell. 2021 May 17;56(10):1498-1511.e7.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Robert N. Hawthorne, Adriana Blazeski, Justin Lowenthal, Suraj Kannan, Roald Teuben, Deborah DiSilvestre, Justin Morrissette-McAlmon, Jeffrey E. Saffitz, Kenneth R. Boheler, Cynthia A. James, Stephen P. Chelko, Gordon Tomaselli and Leslie Tung

Altered Electrical, Biomolecular, and Immunologic Phenotypes in a Novel Patient-Derived Stem Cell Model of Desmoglein-2 Mutant ARVC.

J. Clin. Med. 2021, 10(14), 3061;
MiCAM ULTIMA Cultured Cell Voltage Sensitive Dye Calcium Sensitive Dye


Uma Mahesh R. Avula, Lea Melki, Jared S. Kushner, Stephanie Liang, and Elaine Y. Wan

Theoretical Models and Computational Analysis of Action Potential Dispersion for Cardiac Arrhythmia Risk Stratification.

Front Cardiovasc Med. 2021; 8: 649489.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Lianguo Wang, Rachel C. Myles, I-Ju Lee, Donald M. Bers, and Crystal M. Ripplinger

Role of Reduced Sarco-Endoplasmic Reticulum Ca2+-ATPase Function on Sarcoplasmic Reticulum Ca2+ Alternans in the Intact Rabbit Heart.

Front Physiol. 2021; 12: 656516.
MiCAM ULTIMA Dual Camera System Isolated Heart Voltage Sensitive Dye Calcium Sensitive Dye


Yeon Sik Choi, Rose T Yin, Anna Pfenniger, Jahyun Koo, Raudel Avila, K Benjamin Lee, Sheena W Chen, Geumbee Lee, Gang Li, Yun Qiao, Alejandro Murillo-Berlioz, Alexi Kiss, Shuling Han, Seung Min Lee, Chenhang Li, Zhaoqian Xie, Yu-Yu Chen, Amy Burrell, Beth Geist, Hyoyoung Jeong, Joohee Kim, Hong-Joon Yoon, Anthony Banks, Seung-Kyun Kang, Zheng Jenny Zhang, Chad R Haney, Alan Varteres Sahakian, David Johnson, Tatiana Efimova, Yonggang Huang, Gregory D Trachiotis, Bradley P Knight, Rishi K Arora, Igor R Efimov, John A Rogers

Fully implantable and bioresorbable cardiac pacemakers without leads or batteries.

Nat Biotechnol. 2021 Jun 28.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Zhiyuan Chen, Nicolas Boyajian, Zexu Lin, Rose T. Yin, Sofian N. Obaid, Jinbi Tian, Jaclyn A. Brennan, Sheena W. Chen, Alana N. Miniovich, Leqi Lin, Yarong Qi, Xitong Liu, Igor R. Efimov, Luyao Lu

Flexible and Transparent Metal Nanowire Microelectrode Arrays and Interconnects for Electrophysiology, Optogenetics, and Optical Mapping.

Adv. Mater. Technol. 2021, 6, 2100225.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Ge Zhan, Fang Wang, Yun-qi Ding, Xiang-hua Li, Yue-xin Li, Zheng-rong Zhao, Jia-xin Li, Yan Liu, Xin Zhao, Cai-chuan Yan, Bao-xin Li

Rutaecarpine targets hERG channels and participates in regulating electrophysiological properties leading to ventricular arrhythmia.

J Cell Mol Med. 2021;00:1–12.
MiCAM05 ULTIMA Isolated Heart Voltage Sensitive Dye 


De-sheng Li, Gen-long Xue, Ji-ming Yang, Chang-zhu Li, Rui-xin Zhang, Tao Tian, Zheng Li, Ke-wei Shen, Yang Guo, Xue-ning Liu, Jin Wang, Yan-jie Lu & Zhen-wei Pan

Knockout of interleukin-17A diminishes ventricular arrhythmia susceptibility in diabetic mice via inhibiting NF-κB-mediated electrical remodeling.

Acta Pharmacologica Sinica (2021)
MiCAM05 ULTIMA Isolated Heart Voltage Sensitive Dye 


Duanyang Xie, Ke Xiong, Xuling Su, Guanghua Wang, Qiang Ji, Qicheng Zou, Lingling Wang, Yi Liu, Dandan Liang, Jinfeng Xue, Luxin Wang, Xueting Gao, Xingdong Gu, Hongyu Liu, Xiaoyu He, Li Li, Jian Yang, Youming Lu, Luying Peng & Yi-Han Chen

Identification of an endogenous glutamatergic transmitter system controlling excitability and conductivity of atrial cardiomyocytes.

Cell Research volume 31, pages951–964 (2021)
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Mohammed Ali Azam, Praloy Chakraborty, Daoyuan Si, BeiBei Du, Stéphane Massé, Patrick F H Lai, Andrew C T Ha, Kumaraswamy Nanthakumar

Anti-arrhythmic and inotropic effects of empagliflozin following myocardial ischemia.

Life Sci. 2021 Jul 1;276:119440.
MiCAM ULTIMA Isolated Heart Calcium Sensitive Dye


Larry Scott Jr, Anke C Fender, Arnela Saljic, Luge Li, Xiaohui Chen, Xiaolei Wang, Dominik Linz, Jilu Lang, Mathias Hohl, Darragh Twomey, Thuy T Pham, Rodrigo Diaz-Lankenau, Mihail G Chelu, Markus Kamler, Mark L Entman, George E Taffet, Prashanthan Sanders, Dobromir Dobrev, Na Li

NLRP3 inflammasome is a key driver of obesity-induced atrial arrhythmias.

Cardiovasc Res. 2021 Jun 16;117(7):1746-1759.
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Kenneth Williams, Timothy Liang, Stéphane Massé, Safwat Khan, Rupal Hatkar, Gordon Keller, Kumaraswamy Nanthakumar, Sara S. Nunes

A 3-D Human Model of Complex Cardiac Arrhythmias.

Acta Biomaterialia Available online 10 March 2021
MiCAM ULTIMA Cultured Cell Calcium Sensitive Dye


Willem J. de Lange, Emily T. Farrell, Caroline R. Kreitzer, Derek R. Jacobs, Di Lang, Alexey V. Glukhov, and J. Carter Ralphe

Human iPSC engineered cardiac tissue platform faithfully models important cardiac physiology.

Am J Physiol Heart Circ Physiol. 2021 Feb 19.
MiCAM ULTIMA Cultured Cell Calcium Sensitive Dye


Yu Jiang, Si-Jia Sun, Zhe Zhen, Rui Wei, Nannan Zhang, Song-Yan Liao & Hung-Fat Tse

Myocardial repair of bioengineered cardiac patches with decellularized placental scaffold and human-induced pluripotent stem cells in a rat model of myocardial infarction.

Stem Cell Res Ther 12, 13 (2021).
MiCAM ULTIMA Cultured Cell Calcium Sensitive Dye


Hugo Poulin, Aurélie Mercier, Mohammed Djemai, Valérie Pouliot, Isabelle Deschenes, Mohamed Boutjdir, Jack Puymirat & Mohamed Chahine

iPSC-derived cardiomyocytes from patients with myotonic dystrophy type 1 have abnormal ion channel functions and slower conduction velocities.

Scientific Reports volume 11, Article number: 2500 (2021)
MiCAM03-N256 Cultured Cell Voltage Sensitive Dye 


Jun Li, Jong-Kook Lee, Keiko Miwa, Yuki Kuramoto, Kiyoshi Masuyama, Hideki Yasutake, Satoki Tomoyama, Hiroyuki Nakanishi, and Yasushi Sakata

Scaffold-Mediated Developmental Effects on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Are Preserved After External Support Removal.

Front Cell Dev Biol. 2021; 9: 591754.
MiCAM02-HR Cultured Cell Voltage Sensitive Dye 


Andy On-Tik Wong, Bimal Gurung, Wing Sum Wong, Suet Yee Mak, Wan Wai Tse, Chloe M. Li, Deborah K. Lieu, Kevin D. Costa, Ronald A. Li, and Roger J. Hajjar

Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues.

J Mol Cell Cardiol. 2021 Apr; 153: 106–110.
MiCAM03-N256 Cultured Cell Voltage Sensitive Dye 


D. Ryan King, Michael Entz II, Grace A. Blair, Ian Crandell, Alexandra L. Hanlon, Joyce Lin, Gregory S. Hoeker & Steven Poelzing

The conduction velocity-potassium relationship in the heart is modulated by sodium and calcium.

Pflügers Archiv - European Journal of Physiology volume 473, pages557–571(2021)
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Veronika Olejnickova, Matej Kocka, Alena Kvasilova, Hana Kolesova, Adam Dziacky, Tom Gidor, Lihi Gidor, Barbora Sankova, Martina Gregorovicova, Robert G. Gourdie and David Sedmera

Gap Junctional Communication via Connexin43 between Purkinje Fibers and Working Myocytes Explains the Epicardial Activation Pattern in the Postnatal Mouse Left Ventricle.

Int. J. Mol. Sci. 2021, 22(5), 2475;
MiCAM ULTIMA Isolated Heart Voltage Sensitive Dye 


Roman Y. Medvedev, Jose L. Sanchez-Alonso, Catherine A. Mansfield, Aleksandra Judina, Alice J. Francis, Christina Pagiatakis, Natalia Trayanova, Alexey V. Glukhov, Michele Miragoli, Giuseppe Faggian & Julia Gorelik

Local hyperactivation of L-type Ca2+ channels increases spontaneous Ca2+ release activity and cellular hypertrophy in right ventricular myocytes from heart failure rats.

Scientific Reports volume 11, Article number: 4840 (2021)
MiCAM ULTIMA Cultured Cell Calcium Sensitive Dye


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Cardiac Imaging